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西安交通大学第一附属医院精准医学研究中心诚聘海内外英才
发布时间:2019年02月01日 15:19   责任编辑:人力资源部   (点击: )

Multiple positions available at the Center of Precision Medicine

The First Affiliated Hospital of Xian Jiaotong University

The First Affiliated Hospital of Xi'an Jiaotong University is alarge and comprehensive hospital combining patient health care, teaching, andscientific research.It is one of the select hospitals honored with the level-three class-A rank in China, and has been one of the first national "One Hundred Exemplary Hospitals."The Center of Precision Medicine is a newly established, state-of-the-art Research Center through international collaborations between theFirst Affiliated Hospital of Xi'an Jiaotong Universityand Dr. Charles Lee, the Scientific Director of The Jackson Laboratory for Genomic Medicine (JAX-GM) in Farmington, CT, USA.There are three major key components of the Center of Precision Medicine, Laboratory of Clinical Genetics and Genomics, Laboratory of Bioinformatics, and Laboratory of Microbiome and Patient-Derived Xenograft.

Laboratory of Clinical Genetics and GenomicsMajor technical platforms in this group includenext generation sequencing (NGS), droplet digital PCR (ddPCR) and genome-wide microarray technologies. Research directions include:(1) Conduct cutting-edge translational research, including discovering new biomarkers in Cancer Genomics. (2) Studying the molecular mechanisms of diseases with unknown etiology. (3) Development and validation of novel clinical assays.

Laboratory of BioinformaticsThe Research directions and objectives of the group is developing algorithms and building bioinformatics pipelines for high-throughput sequencing analysis, cancer genome analysis, disease-related structural variation analysis, single-cell sequencing analysis, and microbiological data analysis.

Laboratory of Microbiome and Patient-Derived Xenograft Research directions and objectives in this group include medical microbiology, cancer immunology and development of patient-derived-xenograft animal model. Firstly, we are keen to understand human microbiome meta-genome research and the effect of tumor microenvironment to cancer immunotherapy. Secondly, we use PDX model as a platform to understand mechanisms of cancer immunotherapy and drug discovery.

1.Job descriptions

Lab

Openings

Qualifications

Responsibilities

# of openings

Contact

Lab. of Clinical Genetics and Genomics

Research Assistant

·Good educational backgroundwith a Bachelor degree or Master degree in molecular biology, cell biology, biochemistry, microbiology and immunology, genetics, laboratory medicine, or other relevant fields.

·Familiar with common research techniques, such as cell culture, DNA/RNA extractions, PCR/RT-PCR/ddPCR, DNA/RNA sequencing, microarray, etc.

·Good work ethics (responsible and diligent).

·Strong aptitude for learning.

·Attention to details.

·Good with record keeping.

·Basic computer application skills, such as Microsoft Word, Excel, PowerPoint.

·Perform various experiments and assays under the supervision of the lab manager and/or other senior staff members at the lab;

·Collect, analyze, and summarize experimental data for case reports, paper publications and/or grant applications.

·Assisting with the purchase and maintenance of the lab equipment as well as the ordering of reagents and suppliers.

·Assisting with manuscript and grant writing and submission.

5

Dr. Zhang: cszhang99@xjtu.edu.cn

Laboratory Manager

·Excellent educational background with a Bachelor degree, Master degree or Doctoral degree in the biomedical or medical sciences, with expertise in molecular biology, cell biology, genetics and genomics, biochemistry, microbiology, immunology, laboratory medicine, or related areas.

·Strong interest in translational and clinical research.

·Suitable working experience in biomedical research laboratories. At least 5 years-working experience for the candidates with a bachelor degree; At least two years-working experience for the candidates with a Master degree.

·Familiar with common research techniques, such as cell culture, DNA/RNA extractions, PCR/RT-PCR/ddPCR, DNA/RNA sequencing, microarray, etc.

·Good experimental skills, including trouble shooting skills.

·Good management and leadership skills and enjoy team work.

·Strong organizational and operational skills (ability to coordinate with other groups, prioritize tasks and meeting deadlines).

·Customer service and quality oriented.

·Excellent communication and interpersonal skills and be fluent in English (written and spoken).

·Good work ethics (responsible and diligent)

·Basic computer application skills, such as Microsoft Word, Excel, PowerPoint.

Preferred qualifications:

·Experience overseeing lab safety and adherence to regulatory guidelines strongly preferred.

·Experience in molecular and/or NGS sequencing assay and process development, validation, implementation and scale-up strongly preferred.

·Help the Lab Director to oversee the routine operation of the lab while ensuring high data quality, integrity and meeting the deadlines;

·Supervise and coordinate the routine inter and intra lab activities including but not limited to sample processing, process, protocol and instrumentation implementations and optimization, SOP development and validations;

·In charge of the purchase and maintenance of the lab equipment as well as the ordering the reagents and suppliers.

·In charge of the lab safety issues.

·Assisting the training of lab members.

·Assisting with manuscript and grant writing and submission.

1

Lab. Of Bioinformatics

Senior Computational Scientist / Computational Scientist

·Good educational background with a master (computational scientist) or doctoral degree (senior computational scientist) in bioinformatics, biostatistics, computer science and related disciplines.

·Capable to develop scientific research independently.

·Aware of the developments in the field and have innovative ideas and research strategic.

·Experience:whole-genome, whole-exome, RNA sequence analysis skills, single-cell sequencing or microbiome data analysis skills.

·Programming skill:Having proficiency in Linux and in at least one programming language. Familiar with common molecular biology databases and bioinformatics analysis software.

·Having good communication skills in English.

·Publishing one high-impact international journal papers.

·Performing genomics data analysis.

·Optional:Leading one national research or one provincial research grant.

3

Dr. Lee:

wanping.lee@xjtu.edu.cn

Lab. of Microbiome and Patient-Derived Xenograft

Research Assistant

·Good educational backgroundwith a Bachelor degree or Master degree in molecular biology, cell biology, biochemistry, microbiology, immunology, genetics, laboratory medicine, or other relevant fields.

·Familiar with common research techniques in molecular biology and cell culture.

·Experience working with mouse models is preferable.

·Good work ethics (responsible and diligent).

·Strong aptitude for learning and attention to details.

·Basic computer application skills, such as Microsoft Word, Excel, PowerPoint.

·Perform various experiments and assays under the supervision of the senior lab members.

·Collect, analyze and summarize experimental data, paper publications and/or grant applications.

·Assisting with manuscript and grant writing and submission.

·Assisting the purchase and maintenance of the lab equipment as well as the ordering of supplies and reagents.

3

Dr. Chen:

chunti.chen@jax.org

2.Applications

1)CV including education and working experiences, list of publications, list of research projects or grants, awards, etc.

2)At least two representative papers.

3)Please provide the name and contact information of two references (please specify the relationship between the applicant and the reference).

Please submit your applications to each leader of the lab if you are interested in any position.

 

 

Human Resource

The First Affiliated Hospital of Xi’an Jiaotong University

February1th, 2019

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